Chi-Square Test Examples in Healthcare Studies

Explore practical examples of chi-square tests in healthcare studies to understand data analysis applications.
By Jamie

Understanding the Chi-Square Test in Healthcare Studies

The Chi-Square test is a statistical method used to determine if there is a significant association between categorical variables. In healthcare, this analysis is crucial for understanding patient outcomes, treatment effectiveness, and demographic relationships. Here, we present three diverse and practical examples of the chi-square test in healthcare studies to illustrate its application and relevance.

Example 1: Association Between Smoking Status and Lung Cancer Diagnosis

Context

A healthcare study aimed to investigate whether there is a significant association between smoking status (smoker, non-smoker) and the diagnosis of lung cancer (positive, negative) among patients.

In this study, researchers collected data from 200 patients, categorizing them based on their smoking habits and lung cancer diagnosis.

Smoking Status Lung Cancer Positive Lung Cancer Negative Total
Smoker 60 40 100
Non-Smoker 10 90 100
Total 70 130 200

Using the chi-square test, the researchers calculated:

  • Expected frequencies
  • Chi-square statistic
  • p-value

The results indicated a significant association between smoking status and lung cancer diagnosis (p < 0.01), confirming the hypothesis that smokers are at a higher risk for lung cancer.

Notes

This example highlights the importance of understanding lifestyle factors like smoking in relation to serious health conditions. Variations could include exploring different types of cancer or incorporating other risk factors.

Example 2: Gender Differences in Vaccine Uptake

Context

A public health study examined the relationship between gender (male, female) and vaccine uptake (vaccinated, not vaccinated) for a specific disease, such as influenza. Researchers aimed to identify potential disparities in vaccination rates between genders.

Data were collected from a sample of 500 individuals, categorized by gender and vaccination status.

Gender Vaccinated Not Vaccinated Total
Male 150 100 250
Female 200 50 250
Total 350 150 500

The researchers conducted a chi-square test to evaluate if there was a significant difference in vaccine uptake between male and female participants. The analysis showed a p-value of 0.03, indicating a statistically significant difference.

Notes

This example illustrates how gender may influence health behavior like vaccination. Future studies can explore factors such as age or socioeconomic status to provide deeper insights.

Example 3: Effect of Educational Intervention on Diabetes Management

Context

In a healthcare initiative aimed at improving diabetes management, researchers assessed whether an educational intervention (received, not received) had an impact on patients’ control of their blood sugar levels (controlled, uncontrolled). The study included 300 diabetic patients, half of whom received the educational program.

Data was organized as follows:

Intervention Blood Sugar Controlled Blood Sugar Uncontrolled Total
Received Education 120 30 150
Not Received Education 60 90 150
Total 180 120 300

The chi-square test was performed, revealing a p-value of 0.01, suggesting that the educational intervention significantly improved blood sugar control among participants.

Notes

This example demonstrates the effectiveness of educational programs in healthcare settings. Variations could include analyzing different chronic conditions or the impact of different types of interventions.